Bjerkandera adusta is a widely distributed wood decay fungus commonly associated with the decomposition of hardwoods. Microscopic thread-like hyphae colonize and degrade dead wood, and visually striking shelf-like fruiting bodies often appear on the surface. During the decay process, all components of the wood cell walls are degraded including the cellulose, hemicellulose and recalcitrant lignin. Accordingly, this species is often referred to as a 'white-rot' fungus and related to other sequenced fungi such as Phanerochaete chrysosporium, Cerioporiopsis subvermispora, and Trametes versicolor. Comparative analyses of these species reveal variations in the mechanism(s) by which lignocellulose is degraded, although it is generally thought that extracellular oxidative mechanisms play a crucial role in lignin depolymerization. The remarkable oxidation potential of the secreted peroxidases has attracted considerable attention and, in addition to plant cell wall deconstruction, B. adusta has shown considerable promise in the degradation of a wide range of environmental pollutants.