Xenopus tropicalis v4.1
TRANSCRIPT ANNOTATION 
Xentr4/scaffold_12:945282-948915 estExt_Genewise1.C_120058 Hide 
AttributeValueCreatorAction
Name  
Description  
Model Notes  
DeflinePutative ortholog of tRNA pseudouridine synthase A (EC 5.4.99.12) (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I), 1 of 1Daniel Rokhsar 
DispositionCatalogAUTOMATIC 
 tentativeDaniel Rokhsar 
Literature  
Assessment
 ? 
NoteCreatorAction
EST evidence  
Needs GO  
EvidenceTypeCreatorAction
 

FUNCTIONAL (PROTEIN) ANNOTATION
User-Assigned Ontology       
ASPECT DETAILS
function
      
process
      
component
      
enzyme
      
kog
KOG2553
Pseudouridylate synthase
NULL ISSNULLestExt_Genewise1.C_120058Daniel Rokhsar 
Automatic Ontology and Best Protein Alignments for transcript 265639
Automatic Ontology
ASPECT
GO/ECSUPPORTAction
function
4730  Catalysis of the reaction: uracil + D-ribose 5-phosphate = pseudouridine 5'-phosphate + H2O.IPR001406  tRNA pseudouridine synthase 
process
8033  The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.IPR001406  tRNA pseudouridine synthase 

High Scoring Alignments 

Hs13376820  [none]

view alignment    
GO/EC Classification
Score
Evalue
% id
% target
% model
 
1359
0.0
75%
83%
97%

gi|23503104|sp|Q9Y606|TRUA_HUMAN
tRNA pseudouridine synthase A (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I)  [Homo sapiens]

view alignment    view info
GO/EC Classification
Score
Evalue
% id
% target
% model
MF16829: Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
MF4730: Catalysis of the reaction: uracil + D-ribose 5-phosphate = pseudouridine 5'-phosphate + H2O.
BP8033: The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
CC5634: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1359
0.0
75%
83%
97%

gi|8134771|sp|Q9WU56|TRUA_MOUSE
tRNA pseudouridine synthase A (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I)  [Mus musculus]

view alignment    view info
GO/EC Classification
Score
Evalue
% id
% target
% model
MF16829: Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
MF4730: Catalysis of the reaction: uracil + D-ribose 5-phosphate = pseudouridine 5'-phosphate + H2O.
BP8033: The process by which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
CC5634: A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1342
0.0
73%
84%
97%

rno:304567
LOC304567; similar to pseudouridine synthase 1  [Rattus norvegicus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
1337
0.0
73%
84%
97%

gi|70166645|ref|NP_079491.2|
pseudouridylate synthase 1 isoform 1 [Homo sapiens] >gi|18027830|gb|AAL55876.1| unknown [Homo sapiens]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
1314
0.0
75%
77%
97%

gi|4455035|gb|AAD21042.1|
pseudouridine synthase 1 [Homo sapiens]

view alignment    view info
GO/EC Classification
Score
Evalue
% id
% target
% model
 
1314
0.0
75%
90%
97%

gi|70166634|ref|NP_001002020.1|
pseudouridylate synthase 1 isoform 2 [Homo sapiens] >gi|70166599|ref|NP_001002019.1| pseudouridylate synthase 1 isoform 2 [Homo sapiens] >gi|17939636|gb|AAH19320.1| Pseudouridylate synthase 1 [Homo sapiens] >gi|12804097|gb|AAH02901.1| Pseudouridylate synthase 1, isoform 2 [Homo sapiens] >gi|14550510|gb|AAH09505.1| Pseudouridylate synthase 1, isoform 1 [Homo sapiens] >gi|23503104|sp|Q9Y606|TRUA_HUMAN tRNA pseudouridine synthase A (tRNA-uridine isomerase I) (tRNA pseudouridylate synthase I)

view alignment    view info
GO/EC Classification
Score
Evalue
% id
% target
% model
 
1314
0.0
75%
83%
97%

gi|50756277|ref|XP_415090.1|
PREDICTED: similar to tRNA pseudouridine synthase A (Pseudouridylate synthase I) (Pseudouridine synthase I) (Uracil hydrolyase) [Gallus gallus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
1302
0.0
76%
81%
98%

gi|11464733|gb|AAG35307.1|
pseudouridine synthase 1 [Mus musculus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
1300
0.0
70%
85%
97%

gi|70906468|ref|NP_001020732.1|
pseudouridine synthase 1 isoform 1 [Mus musculus]

view alignment    view info
GO/EC Classification
Score
Evalue
% id
% target
% model
 
1300
0.0
70%
79%
97%