Xenopus tropicalis v4.1
TRANSCRIPT ANNOTATION 
Xentr4/scaffold_435:629603-655325 e_gw1.435.123.1 Hide 
AttributeValueCreatorAction
Name  
Description  
Model Notes  
Defline  
Disposition  
Literature  
Assessment
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NoteCreatorAction
EST evidence  
Needs GO  
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FUNCTIONAL (PROTEIN) ANNOTATION
User-Assigned Ontology       
ASPECT DETAILS
function
      
process
      
component
      
enzyme
      
kog
      
Automatic Ontology and Best Protein Alignments for transcript 374943
Automatic Ontology
ASPECT
GO/ECSUPPORTAction
function
4672  Catalysis of the transfer of a phosphate group, usually from ATP, to a protein substrate.IPR000719  Protein kinase 
4674  Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.IPR002290  Serine/threonine protein kinase 
4713  Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.IPR001245  Tyrosine protein kinase 
 IPR008266  Tyrosine protein kinase, active site 
5006  Combining with an epidermal growth factor to initiate a change in cell activity.IPR000494  Epidermal growth-factor receptor (EGFR), L domain 
5524  Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.IPR002011  Receptor tyrosine kinase, class II 
 IPR008266  Tyrosine protein kinase, active site 
 IPR002290  Serine/threonine protein kinase 
 IPR000719  Protein kinase 
 IPR001245  Tyrosine protein kinase 
 IPR006211  Furin-like cysteine rich region 
 IPR000719  Protein kinase 
process
6468  The process of introducing a phosphoric group on to a protein.IPR001245  Tyrosine protein kinase 
 IPR000719  Protein kinase 
 IPR001245  Tyrosine protein kinase 
 IPR006211  Furin-like cysteine rich region 
 IPR002290  Serine/threonine protein kinase 
 IPR000719  Protein kinase 
 IPR002011  Receptor tyrosine kinase, class II 
 IPR008266  Tyrosine protein kinase, active site 
7169  The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.IPR006211  Furin-like cysteine rich region 
 IPR002011  Receptor tyrosine kinase, class II 
component
16020  Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.IPR002011  Receptor tyrosine kinase, class II 
 IPR000494  Epidermal growth-factor receptor (EGFR), L domain 
 IPR006211  Furin-like cysteine rich region 

High Scoring Alignments 

gi|38014424|gb|AAH60457.1|
MGC68585 protein [Xenopus laevis]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
5325
0.0
83%
84%
100%

gi|31657140|ref|NP_055030.1|
insulin receptor-related receptor precursor [Homo sapiens] >gi|55662088|emb|CAH70009.1| insulin receptor-related receptor [Homo sapiens] >gi|12644000|sp|P14616|INSRR_HUMAN Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3848
0.0
60%
82%
95%

gi|186555|gb|AAC31759.1|
insulin receptor-related receptor [Homo sapiens]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3848
0.0
60%
84%
95%

gi|106736|pir||B36502
insulin receptor-related receptor - human (fragment)  [Homo sapiens]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3834
0.0
60%
84%
95%

gi|124908|sp|P14617|INSRR_CAVPO
Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] >gi|387060|gb|AAA37044.1| insulin receptor-related receptor precursor  [Cavia porcellus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3791
0.0
61%
81%
94%

gi|62643733|ref|XP_574972.1|
PREDICTED: insulin receptor-related receptor [Rattus norvegicus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3781
0.0
60%
81%
94%

gi|57089537|ref|XP_547526.1|
PREDICTED: similar to Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Canis familiaris]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3766
0.0
60%
81%
94%

gi|20177942|sp|Q9WTL4|INSRR_MOUSE
Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] >gi|6754362|ref|NP_035962.1| insulin receptor-related receptor [Mus musculus] >gi|4903002|dbj|BAA77835.1| insulin receptor-related receptor [Mus musculus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3737
0.0
59%
81%
94%

hsa:3645
INSRR; insulin receptor-related receptor [EC:2.7.10.1] [KO:K05086]  [Homo sapiens]

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GO/EC Classification
Score
Evalue
% id
% target
% model
EC2.7.10.1: receptor protein-tyrosine kinase
3709
0.0
67%
82%
95%

mmu:23920
Insrr; insulin receptor-related receptor [EC:2.7.10.1] [KO:K05086]  [Mus musculus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
EC2.7.10.1: receptor protein-tyrosine kinase
3576
0.0
65%
81%
94%