Xenopus tropicalis v4.1
TRANSCRIPT ANNOTATION 
Xentr4/scaffold_435:629603-655115 gw1.435.29.1 Hide 
AttributeValueCreatorAction
Name  
Description  
Model Notes  
Defline  
Disposition  
Literature  
Assessment
 ? 
NoteCreatorAction
EST evidence  
Needs GO  
EvidenceTypeCreatorAction
 

FUNCTIONAL (PROTEIN) ANNOTATION
User-Assigned Ontology       
ASPECT DETAILS
function
      
process
      
component
      
enzyme
      
kog
      
Automatic Ontology and Best Protein Alignments for transcript 40226
Automatic Ontology
ASPECT
GO/ECSUPPORTAction
function
4672  Catalysis of the transfer of a phosphate group, usually from ATP, to a protein substrate.IPR000719  Protein kinase 
4674  Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate.IPR002290  Serine/threonine protein kinase 
4713  Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.IPR001245  Tyrosine protein kinase 
 IPR008266  Tyrosine protein kinase, active site 
5006  Combining with an epidermal growth factor to initiate a change in cell activity.IPR000494  Epidermal growth-factor receptor (EGFR), L domain 
5524  Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.IPR002011  Receptor tyrosine kinase, class II 
 IPR008266  Tyrosine protein kinase, active site 
 IPR002290  Serine/threonine protein kinase 
 IPR000719  Protein kinase 
 IPR001245  Tyrosine protein kinase 
 IPR006211  Furin-like cysteine rich region 
 IPR000719  Protein kinase 
process
6468  The process of introducing a phosphoric group on to a protein.IPR001245  Tyrosine protein kinase 
 IPR000719  Protein kinase 
 IPR001245  Tyrosine protein kinase 
 IPR006211  Furin-like cysteine rich region 
 IPR002290  Serine/threonine protein kinase 
 IPR000719  Protein kinase 
 IPR002011  Receptor tyrosine kinase, class II 
 IPR008266  Tyrosine protein kinase, active site 
7169  The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.IPR006211  Furin-like cysteine rich region 
 IPR002011  Receptor tyrosine kinase, class II 
component
16020  Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.IPR002011  Receptor tyrosine kinase, class II 
 IPR000494  Epidermal growth-factor receptor (EGFR), L domain 
 IPR006211  Furin-like cysteine rich region 

High Scoring Alignments 

gi|38014424|gb|AAH60457.1|
MGC68585 protein [Xenopus laevis]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
5021
0.0
83%
79%
100%

gi|186555|gb|AAC31759.1|
insulin receptor-related receptor [Homo sapiens]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3811
0.0
61%
83%
100%

gi|31657140|ref|NP_055030.1|
insulin receptor-related receptor precursor [Homo sapiens] >gi|55662088|emb|CAH70009.1| insulin receptor-related receptor [Homo sapiens] >gi|12644000|sp|P14616|INSRR_HUMAN Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3811
0.0
61%
81%
100%

gi|106736|pir||B36502
insulin receptor-related receptor - human (fragment)  [Homo sapiens]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3797
0.0
60%
83%
100%

gi|124908|sp|P14617|INSRR_CAVPO
Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] >gi|387060|gb|AAA37044.1| insulin receptor-related receptor precursor  [Cavia porcellus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3791
0.0
61%
81%
100%

gi|62643733|ref|XP_574972.1|
PREDICTED: insulin receptor-related receptor [Rattus norvegicus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3778
0.0
60%
81%
100%

gi|57089537|ref|XP_547526.1|
PREDICTED: similar to Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Canis familiaris]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3766
0.0
60%
81%
100%

gi|20177942|sp|Q9WTL4|INSRR_MOUSE
Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] >gi|6754362|ref|NP_035962.1| insulin receptor-related receptor [Mus musculus] >gi|4903002|dbj|BAA77835.1| insulin receptor-related receptor [Mus musculus]

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GO/EC Classification
Score
Evalue
% id
% target
% model
 
3734
0.0
59%
81%
100%

hsa:3645
INSRR; insulin receptor-related receptor [EC:2.7.10.1] [KO:K05086]  [Homo sapiens]

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GO/EC Classification
Score
Evalue
% id
% target
% model
EC2.7.10.1: receptor protein-tyrosine kinase
3686
0.0
67%
81%
100%

gi|12644000|sp|P14616|INSRR_HUMAN
Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]  [Homo sapiens]

view alignment    view info
GO/EC Classification
Score
Evalue
% id
% target
% model
MF16740: Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
MF4672: Catalysis of the transfer of a phosphate group, usually from ATP, to a protein substrate.
MF4713: Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
MF4872: Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
MF5006: Combining with an epidermal growth factor to initiate a change in cell activity.
MF5524: Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
BP6468: The process of introducing a phosphoric group on to a protein.
BP7169: The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand.
CC16020: Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
CC16021: Penetrating at least one phospholipid bilayer of a membrane. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence spans the membrane.
CC5887: Penetrating at least one phospholipid bilayer of a plasma membrane. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer.
3686
0.0
67%
81%
100%