Automatic Ontology |
ASPECT |
|
function |
4672 Catalysis of the transfer of a phosphate group, usually from ATP, to a protein substrate. | IPR000719 Protein kinase | | 4674 Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate. | IPR002290 Serine/threonine protein kinase | | 4713 Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. | IPR001245 Tyrosine protein kinase | | | IPR008266 Tyrosine protein kinase, active site | | 5006 Combining with an epidermal growth factor to initiate a change in cell activity. | IPR000494 Epidermal growth-factor receptor (EGFR), L domain | | 5524 Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | IPR002011 Receptor tyrosine kinase, class II | | | IPR008266 Tyrosine protein kinase, active site | | | IPR002290 Serine/threonine protein kinase | | | IPR000719 Protein kinase | | | IPR001245 Tyrosine protein kinase | | | IPR006211 Furin-like cysteine rich region | | | IPR000719 Protein kinase | |
|
process |
6468 The process of introducing a phosphoric group on to a protein. | IPR001245 Tyrosine protein kinase | | | IPR000719 Protein kinase | | | IPR001245 Tyrosine protein kinase | | | IPR006211 Furin-like cysteine rich region | | | IPR002290 Serine/threonine protein kinase | | | IPR000719 Protein kinase | | | IPR002011 Receptor tyrosine kinase, class II | | | IPR008266 Tyrosine protein kinase, active site | | 7169 The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. | IPR006211 Furin-like cysteine rich region | | | IPR002011 Receptor tyrosine kinase, class II | |
|
component |
16020 Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. | IPR002011 Receptor tyrosine kinase, class II | | | IPR000494 Epidermal growth-factor receptor (EGFR), L domain | | | IPR006211 Furin-like cysteine rich region | |
|
High Scoring Alignments |
gi|38014424|gb|AAH60457.1| MGC68585 protein [Xenopus laevis]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
|
5021 |
0.0 |
83% |
79% |
100% |
|
gi|186555|gb|AAC31759.1| insulin receptor-related receptor [Homo sapiens]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
|
3811 |
0.0 |
61% |
83% |
100% |
|
gi|31657140|ref|NP_055030.1| insulin receptor-related receptor precursor [Homo sapiens] >gi|55662088|emb|CAH70009.1| insulin receptor-related receptor [Homo sapiens] >gi|12644000|sp|P14616|INSRR_HUMAN Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
|
3811 |
0.0 |
61% |
81% |
100% |
|
gi|106736|pir||B36502 insulin receptor-related receptor - human (fragment) [Homo sapiens]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
|
3797 |
0.0 |
60% |
83% |
100% |
|
gi|124908|sp|P14617|INSRR_CAVPO Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] >gi|387060|gb|AAA37044.1| insulin receptor-related receptor precursor [Cavia porcellus]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
|
3791 |
0.0 |
61% |
81% |
100% |
|
gi|62643733|ref|XP_574972.1| PREDICTED: insulin receptor-related receptor [Rattus norvegicus]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
|
3778 |
0.0 |
60% |
81% |
100% |
|
gi|57089537|ref|XP_547526.1| PREDICTED: similar to Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Canis familiaris]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
|
3766 |
0.0 |
60% |
81% |
100% |
|
gi|20177942|sp|Q9WTL4|INSRR_MOUSE Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] >gi|6754362|ref|NP_035962.1| insulin receptor-related receptor [Mus musculus] >gi|4903002|dbj|BAA77835.1| insulin receptor-related receptor [Mus musculus]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
|
3734 |
0.0 |
59% |
81% |
100% |
|
hsa:3645 INSRR; insulin receptor-related receptor [EC:2.7.10.1] [KO:K05086] [Homo sapiens]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
EC | 2.7.10.1: receptor protein-tyrosine kinase | |
|
3686 |
0.0 |
67% |
81% |
100% |
|
gi|12644000|sp|P14616|INSRR_HUMAN Insulin receptor-related protein precursor (IRR) (IR-related receptor) [Contains: Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain] [Homo sapiens]
view alignment view info |
GO/EC Classification |
Score |
Evalue |
% id |
% target |
% model |
MF | 16740: Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. | | MF | 4672: Catalysis of the transfer of a phosphate group, usually from ATP, to a protein substrate. | | MF | 4713: Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. | | MF | 4872: Combining with an extracellular or intracellular messenger to initiate a change in cell activity. | | MF | 5006: Combining with an epidermal growth factor to initiate a change in cell activity. | | MF | 5524: Interacting selectively with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. | | BP | 6468: The process of introducing a phosphoric group on to a protein. | | BP | 7169: The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. | | CC | 16020: Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. | | CC | 16021: Penetrating at least one phospholipid bilayer of a membrane. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence spans the membrane. | | CC | 5887: Penetrating at least one phospholipid bilayer of a plasma membrane. Also refers to the state of being buried in the bilayer with no exposure outside the bilayer. | |
|
3686 |
0.0 |
67% |
81% |
100% |
|