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Bacillus coagulans 36D1 is a thermo-tolerant and acid-tolerant bacterium. Although some members of this species are found to be cellulose degrading, this particular strain is cellulose-negative. This strain, because of its thermotolerant properties, is more suitable for cost-effective simultaneous saccharification and fermentation of cellulose with supplemental addition of fungal cellulases. Bacillus coagulans 36D1 , a lactic acid producing bacterium, was first identified as a spoilage agent of milk products. This organism can be used in the production of ethanol and lactic acid from cellulose and hemicellulose acid hydrolysate. This organism is not used at present for production of either ethanol or lactic acid and is still in developmental stage. Once engineered to produce ethanol, this bacterium can serve as a biocatalyst for conversion of biomass derived sugars (from cellulose and hemicellulose) to ethanol in a cost-effective manner. Since this bacterium is not used at present, the term, “is also used” is too strong. Bacillus coagulans also produces other commercially important chemicals like cyclodextrins and amylases, and has been used as a probiotic in animal feed. The genome sequence will provide information on the production and regulation of these compounds. |
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