Peptidases • Phlebia brevispora HHB-7030 SS6 v1.0
| Annotations/Genomes | Total | Annotation Description | ||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 Merops | 432 | 287 | 157 | 299 | 407 | 316 | 315 | 304 | 138 | 242 | 450 | 196 | 390 | 158 | 414 | 433 | 149 | 148 | 321 | 5,556 | ||||||||
| 59 | 11 | 6 | 30 | 44 | 33 | 36 | 34 | 17 | 25 | 65 | 20 | 49 | 11 | 36 | 62 | 5 | 8 | 40 | 591 | Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms | ||||||||
| 1 | 1 | 2 | Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane. | |||||||||||||||||||||||||
| 1 | 1 | 3 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 1 | 2 | 2 | 1 | 1 | 1 | 1 | 24 | Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane. | |||||||||
| 5 | 1 | 6 | Water nucleophile; water bound by two Asp | |||||||||||||||||||||||||
| 25 | 15 | 14 | 19 | 16 | 21 | 20 | 18 | 13 | 30 | 18 | 8 | 16 | 16 | 24 | 15 | 14 | 18 | 16 | 336 | Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence | ||||||||
| 9 | 5 | 3 | 3 | 6 | 5 | 6 | 7 | 2 | 3 | 17 | 6 | 4 | 2 | 10 | 4 | 4 | 2 | 8 | 106 | Cysteine nucleophile; catalytic residues in the order His, Cys in sequence | ||||||||
| 1 | 1 | 2 | 3 | 1 | 5 | 1 | 2 | 1 | 1 | 2 | 1 | 1 | 22 | Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence | ||||||||||||||
| 1 | 1 | 1 | 1 | 4 | Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence | |||||||||||||||||||||||
| 1 | 1 | Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence | ||||||||||||||||||||||||||
| 1 | 1 | 1 | 3 | Cysteine nucleophile; catalytic residues in the order His, Cys in sequence | ||||||||||||||||||||||||
| 25 | 2 | 3 | 1 | 1 | 6 | 1 | 39 | Water nucleophile; water bound by Gln and Glu; all endopeptidases | ||||||||||||||||||||
| 2 | 7 | 2 | 3 | 2 | 3 | 3 | 2 | 2 | 3 | 15 | 2 | 3 | 3 | 3 | 2 | 2 | 2 | 2 | 63 | Families of peptidase inhibitors not assigned to clans | ||||||||
| 1 | 1 | |||||||||||||||||||||||||||
| 1 | 1 | 1 | 1 | 4 | ||||||||||||||||||||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 2 | 1 | 1 | 12 | |||||||||||||||||
| 2 | 5 | 2 | 1 | 3 | 2 | 2 | 4 | 7 | 8 | 2 | 3 | 1 | 8 | 2 | 1 | 53 | ||||||||||||
| 2 | 3 | 1 | 2 | 2 | 2 | 3 | 3 | 1 | 1 | 1 | 4 | 2 | 7 | 2 | 2 | 2 | 4 | 44 | Families of metallopeptidases not assigned to clans | |||||||||
| 17 | 30 | 8 | 5 | 15 | 13 | 15 | 13 | 7 | 9 | 20 | 11 | 15 | 10 | 12 | 22 | 9 | 7 | 11 | 249 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp | ||||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 11 | Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His | ||||||||||||||||
| 1 | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 3 | 3 | 5 | 1 | 1 | 1 | 1 | 3 | 27 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu | |||||||||||
| 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | 1 | 15 | Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu | |||||||||||||||
| 7 | 7 | 8 | 10 | 8 | 11 | 9 | 9 | 6 | 7 | 11 | 4 | 8 | 7 | 14 | 9 | 8 | 4 | 9 | 156 | Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu | ||||||||
| 22 | 22 | 13 | 18 | 13 | 13 | 16 | 13 | 7 | 8 | 15 | 3 | 19 | 9 | 27 | 15 | 9 | 6 | 17 | 265 | Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His | ||||||||
| 17 | 8 | 10 | 12 | 15 | 8 | 11 | 14 | 2 | 7 | 11 | 8 | 11 | 8 | 15 | 12 | 10 | 4 | 12 | 195 | Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His. | ||||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 13 | Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site. | ||||||||||||||
| 1 | 1 | 2 | Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH) | |||||||||||||||||||||||||
| 6 | 7 | 5 | 5 | 6 | 7 | 6 | 5 | 4 | 7 | 6 | 1 | 6 | 5 | 6 | 7 | 5 | 5 | 6 | 105 | Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D) | ||||||||
| 1 | 1 | 1 | 3 | Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases | ||||||||||||||||||||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 1 | 7 | Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases | ||||||||||||||||||||
| 18 | 19 | 17 | 23 | 22 | 20 | 22 | 22 | 17 | 17 | 23 | 8 | 21 | 18 | 21 | 22 | 20 | 18 | 24 | 372 | Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme | ||||||||
| 10 | 8 | 3 | 3 | 7 | 7 | 6 | 4 | 3 | 2 | 6 | 3 | 6 | 3 | 5 | 5 | 3 | 1 | 5 | 90 | Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence. | ||||||||
| 2 | 1 | 3 | Serine or threonine nucleophile; N-terminal nucleophile | |||||||||||||||||||||||||
| 19 | 8 | 1 | 10 | 32 | 8 | 11 | 19 | 6 | 31 | 10 | 12 | 2 | 19 | 34 | 1 | 2 | 20 | 245 | Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs | |||||||||
| 134 | 99 | 40 | 102 | 136 | 116 | 112 | 96 | 29 | 77 | 160 | 75 | 145 | 33 | 146 | 178 | 31 | 50 | 105 | 1,864 | Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence | ||||||||
| 5 | 2 | 12 | 5 | 1 | 4 | 2 | 8 | 5 | 8 | 1 | 10 | 6 | 1 | 3 | 1 | 74 | Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence | |||||||||||
| 5 | 2 | 3 | 5 | 4 | 4 | 3 | 3 | 3 | 2 | 3 | 6 | 3 | 4 | 3 | 4 | 3 | 1 | 4 | 65 | Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence | ||||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 17 | Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence | ||||||||||
| 1 | 1 | 2 | Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS. | |||||||||||||||||||||||||
| 4 | 3 | 3 | 3 | 5 | 3 | 3 | 5 | 2 | 1 | 4 | 4 | 3 | 2 | 4 | 3 | 4 | 3 | 59 | Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane | |||||||||
| 1 | 1 | 1 | 1 | 4 | Families of peptidases of unknown catalytic mechanism not assigned to clans | |||||||||||||||||||||||
| 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 18 | ||||||||||
| 32 | 10 | 10 | 14 | 52 | 31 | 14 | 16 | 14 | 17 | 14 | 11 | 48 | 14 | 23 | 13 | 9 | 6 | 22 | 370 | |||||||||
| 1 | 1 | |||||||||||||||||||||||||||
| 1 | 1 | |||||||||||||||||||||||||||
| 1 | 1 | |||||||||||||||||||||||||||
| 1 | 1 | |||||||||||||||||||||||||||
| 2 | 1 | 3 | 2 | 2 | 10 |
